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Ribozyme-mediated, multiplex CRISPR gene editing and CRISPR interference (CRISPRi) in rodent-infectious Plasmodium yoelii

Malaria remains a major global health issue, affecting millions and killing hundreds of thousands of people annually. Efforts to break the transmission cycle of the causal Plasmodium parasite, and to cure those that are afflicted, rely upon functional characterization of genes essential to the paras...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Walker, Michael P., Lindner, Scott E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579477/
https://ncbi.nlm.nih.gov/pubmed/31043479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007121
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