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Ribozyme-mediated, multiplex CRISPR gene editing and CRISPR interference (CRISPRi) in rodent-infectious Plasmodium yoelii

Malaria remains a major global health issue, affecting millions and killing hundreds of thousands of people annually. Efforts to break the transmission cycle of the causal Plasmodium parasite, and to cure those that are afflicted, rely upon functional characterization of genes essential to the paras...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Walker, Michael P., Lindner, Scott E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579477/
https://ncbi.nlm.nih.gov/pubmed/31043479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007121
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