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Elucidating Tau function and dysfunction in the era of cryo-EM
Tau is a microtubule-associated protein involved in the regulation of axonal microtubules in neurons. In pathological conditions, it forms fibrils that are molecular hallmarks of neurological disorders known as tauopathies. In the last 2 years, cryo-EM has given unprecedented high-resolution views o...
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| 發表在: | J Biol Chem |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6579466/ https://ncbi.nlm.nih.gov/pubmed/31088912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.008031 |
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