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Ensemble cryo-EM elucidates the mechanism of translation fidelity
Faithful gene translation depends on accurate decoding, whose structural mechanism remains a matter of debate. Ribosomes decode mRNA codons by selecting cognate aminoacyl-tRNAs delivered by EF-Tu. We present high-resolution structural ensembles of ribosomes with cognate or near-cognate aminoacyl-tRN...
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| 出版年: | Nature |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5657493/ https://ncbi.nlm.nih.gov/pubmed/28538735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22397 |
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