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CRM2DIM: A SAS macro for implementing the Dual-Agent Bayesian Continual Reassessment Method
BACKGROUND AND OBJECTIVE: The continual reassessment method (CRM) is a model-based dose-finding design for single-agent phase I oncology trials. With the advance of targeted therapies in oncology, more and more phase I trials investigate drug combinations rather than a single agent in order to find...
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| Publicado no: | Comput Methods Programs Biomed |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6579114/ https://ncbi.nlm.nih.gov/pubmed/31200907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmpb.2019.04.025 |
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