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Amyloid β Peptide of Alzheimer’s Disease Downregulates Bcl-2 and Upregulates Bax Expression in Human Neurons
Neuronal apoptosis is a suspected cause of neurodegeneration in Alzheimer’s disease (AD). Increased levels of amyloid β peptide (Aβ) induce neuronal apoptosis in vitro and in vivo. The underlying molecular mechanism of Aβ neurotoxicity is not clear. The normal concentration of Aβ in cerebrospinal fl...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6579094/ https://ncbi.nlm.nih.gov/pubmed/8922409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-23-07533.1996 |
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