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Synthetic libraries of shark vNAR domains with different cysteine numbers within the CDR3

The variable domain of New Antigen Receptors (vNAR) from sharks, present special characteristics in comparison to the conventional antibody molecules such as: small size (12–15 kDa), thermal and chemical stability and great tissue penetration, that makes them a good alternative source as therapeutic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cabanillas-Bernal, Olivia, Dueñas, Salvador, Ayala-Avila, Marta, Rucavado, Alexandra, Escalante, Teresa, Licea-Navarro, Alexei F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576789/
https://ncbi.nlm.nih.gov/pubmed/31206542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213394
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