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Nicotinic acetylcholine receptor desensitization is regulated by activation-induced extracellular adenosine accumulation

Adenosine modulation of nicotinic ACh receptor (nAChR) function was studied in primary cultures of rat skeletal muscle. Activation of the nAChR by carbachol increased extracellular adenosine concentration in a dose-dependent manner. Furthermore, carbachol activation of the nicotinic receptor resulte...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Pitchford, S, Day, JW, Gordon, A, Mochly-Rosen, D
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576003/
https://ncbi.nlm.nih.gov/pubmed/1331363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-11-04540.1992
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