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Nicotinic acetylcholine receptor desensitization is regulated by activation-induced extracellular adenosine accumulation

Adenosine modulation of nicotinic ACh receptor (nAChR) function was studied in primary cultures of rat skeletal muscle. Activation of the nAChR by carbachol increased extracellular adenosine concentration in a dose-dependent manner. Furthermore, carbachol activation of the nicotinic receptor resulte...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Pitchford, S, Day, JW, Gordon, A, Mochly-Rosen, D
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6576003/
https://ncbi.nlm.nih.gov/pubmed/1331363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.12-11-04540.1992
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