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Desensitization of Nicotinic Acetylcholine Receptors as a Strategy for Drug Development

The specific pharmacological response evoked by a nicotinic acetylcholine receptor (nAChR) agonist is governed by the anatomical distribution and expression of each receptor subtype and by the stoichiometry of subunits comprising each subtype. Contributing to this complexity is the ability of agonis...

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Detalhes bibliográficos
Main Authors: Buccafusco, Jerry J., Beach, J. Warren, Terry, Alvin V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682277/
https://ncbi.nlm.nih.gov/pubmed/19023041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.145292
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