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Desensitization of Nicotinic Acetylcholine Receptors as a Strategy for Drug Development
The specific pharmacological response evoked by a nicotinic acetylcholine receptor (nAChR) agonist is governed by the anatomical distribution and expression of each receptor subtype and by the stoichiometry of subunits comprising each subtype. Contributing to this complexity is the ability of agonis...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682277/ https://ncbi.nlm.nih.gov/pubmed/19023041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.145292 |
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