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Opiate withdrawal-induced hyperactivity of locus coeruleus neurons is substantially mediated by augmented excitatory amino acid input

Single-cell activity was recorded in the locus coeruleus (LC) of morphine-dependent, halothane-anesthetized rats. Systemic administration of the opiate antagonist naloxone (0.1 mg/kg, i.v.) robustly increased the activity of LC neurons. Local microinjection of naloxone or of its hydrophilic derivati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Akaoka, H, Aston-Jones, G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 1991
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575277/
https://ncbi.nlm.nih.gov/pubmed/1683899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.11-12-03830.1991
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