Direct Facilitatory Role of Paragigantocellularis Neurons in Opiate Withdrawal-Induced Hyperactivity of Rat Locus Coeruleus Neurons: An In Vitro Study

Studies have shown that following opiate withdrawal, the spontaneous discharge rate of locus coeruleus (LC) neurons remarkably increases. Combination of intrinsic mechanisms with extrinsic excitatory modulations mediates the withdrawal-induced hyperactivity of LC neurons. The nucleus paragigantocell...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kaeidi, Ayat, Azizi, Hossein, Javan, Mohammad, Ahmadi Soleimani, S. Mohammad, Fathollahi, Yaghoub, Semnanian, Saeed
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521852/
https://ncbi.nlm.nih.gov/pubmed/26230639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134873
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