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Opiate withdrawal-induced hyperactivity of locus coeruleus neurons is substantially mediated by augmented excitatory amino acid input

Single-cell activity was recorded in the locus coeruleus (LC) of morphine-dependent, halothane-anesthetized rats. Systemic administration of the opiate antagonist naloxone (0.1 mg/kg, i.v.) robustly increased the activity of LC neurons. Local microinjection of naloxone or of its hydrophilic derivati...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Akaoka, H, Aston-Jones, G
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 1991
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6575277/
https://ncbi.nlm.nih.gov/pubmed/1683899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.11-12-03830.1991
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