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Opiate withdrawal and the rat locus coeruleus: behavioral, electrophysiological, and biochemical correlates

We have compared the time course of the behavioral manifestations of opiate withdrawal to the in vivo activity of locus coeruleus (LC) neurons and to increases in the levels of G-proteins, adenylate cyclase, and cAMP-dependent protein kinase known to occur in the LC in opiate-dependent animals. Rats...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Rasmussen, K, Beitner-Johnson, DB, Krystal, JH, Aghajanian, GK, Nestler, EJ
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570391/
https://ncbi.nlm.nih.gov/pubmed/2115910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-07-02308.1990
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