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Opiate withdrawal and the rat locus coeruleus: behavioral, electrophysiological, and biochemical correlates

We have compared the time course of the behavioral manifestations of opiate withdrawal to the in vivo activity of locus coeruleus (LC) neurons and to increases in the levels of G-proteins, adenylate cyclase, and cAMP-dependent protein kinase known to occur in the LC in opiate-dependent animals. Rats...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Rasmussen, K, Beitner-Johnson, DB, Krystal, JH, Aghajanian, GK, Nestler, EJ
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1990
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570391/
https://ncbi.nlm.nih.gov/pubmed/2115910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-07-02308.1990
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