Direct Facilitatory Role of Paragigantocellularis Neurons in Opiate Withdrawal-Induced Hyperactivity of Rat Locus Coeruleus Neurons: An In Vitro Study

Studies have shown that following opiate withdrawal, the spontaneous discharge rate of locus coeruleus (LC) neurons remarkably increases. Combination of intrinsic mechanisms with extrinsic excitatory modulations mediates the withdrawal-induced hyperactivity of LC neurons. The nucleus paragigantocell...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Kaeidi, Ayat, Azizi, Hossein, Javan, Mohammad, Ahmadi Soleimani, S. Mohammad, Fathollahi, Yaghoub, Semnanian, Saeed
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521852/
https://ncbi.nlm.nih.gov/pubmed/26230639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134873
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