Nerve Growth Factor- and Neurotrophin-3-Induced Changes in Nociceptive Threshold and the Release of Substance P from the Rat Isolated Spinal Cord

Acute superfusion of nerve growth factor (NGF; 1–100 ng/ml) through a naive rat spinal cord preparation did not alter basal or electrically evoked release of substance P-like immunoreactivity (SP-LI). In contrast, neurotrophin-3 (NT-3; 1–100 ng/ml), although not modifying SP-LI basal outflow, dose-d...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Malcangio, Marzia, Garrett, Neil E., Cruwys, Simon, Tomlinson, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1997
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573754/
https://ncbi.nlm.nih.gov/pubmed/9334418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-21-08459.1997
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