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CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cord

Cannabinoids have an antinociceptive action in many pain models. We have investigated a possible modulatory role for Type 1 Cannabinoid receptors (CB(1)) on the release of excitatory transmitter Substance P from the adult mouse spinal cord after stimulation of nociceptor terminals by capsaicin. Caps...

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Detalhes bibliográficos
Main Authors: Lever, I J, Malcangio, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573132/
https://ncbi.nlm.nih.gov/pubmed/11786475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704506
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