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CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cord

Cannabinoids have an antinociceptive action in many pain models. We have investigated a possible modulatory role for Type 1 Cannabinoid receptors (CB(1)) on the release of excitatory transmitter Substance P from the adult mouse spinal cord after stimulation of nociceptor terminals by capsaicin. Caps...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lever, I J, Malcangio, M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573132/
https://ncbi.nlm.nih.gov/pubmed/11786475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704506
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