TrkB Signaling Is Required for Postnatal Survival of CNS Neurons and Protects Hippocampal and Motor Neurons from Axotomy-Induced Cell Death

Newborn mice carrying targeted mutations in genes encoding neurotrophins or their signaling Trk receptors display severe neuronal deficits in the peripheral nervous system but not in the CNS. In this study, we show that trkB (−/−) mice have a significant increase in apoptotic cell death in different...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Alcántara, Soledad, Frisén, Jonas, del Río, José Antonio, Soriano, Eduardo, Barbacid, Mariano, Silos-Santiago, Inmaculada
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 1997
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573670/
https://ncbi.nlm.nih.gov/pubmed/9133385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-10-03623.1997
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