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Activation of CPP32-Like Caspases Contributes to Neuronal Apoptosis and Neurological Dysfunction after Traumatic Brain Injury

We examined the temporal profile of apoptosis after fluid percussion-induced traumatic brain injury (TBI) in rats and investigated the potential pathophysiological role of caspase-3-like proteases in this process. DNA fragmentation was observed in samples from injured cortex and hippocampus, but not...

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Vydáno v:J Neurosci
Hlavní autoři: Yakovlev, Alexander G., Knoblach, Susan M., Fan, Lei, Fox, Gerard B., Goodnight, Randyll, Faden, Alan I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573442/
https://ncbi.nlm.nih.gov/pubmed/9295387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-19-07415.1997
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