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Activation of CPP32 and Mch3 alpha in wild-type p53-induced apoptosis.

DNA-damaging agents induce apoptosis primarily by a p53-dependent pathway. LTR6 cells containing a temperature-sensitive p53 were used to dissect further the mechanisms of p53-induced apoptosis. Apoptosis was accompanied by the processing and activation of CPP32 and Mch3 alpha, together with the cle...

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Detalhes bibliográficos
Main Authors: Chandler, J M, Alnemri, E S, Cohen, G M, MacFarlane, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218152/
https://ncbi.nlm.nih.gov/pubmed/9078237
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