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Activation of CPP32-like Proteases Is Not Sufficient to Trigger Apoptosis: Inhibition of Apoptosis by Agents that Suppress Activation of AP24, but Not CPP32-like Activity

The 24-kD apoptotic protease (AP24) is a serine protease that is activated during apoptosis and has the capacity to activate internucleosomal DNA fragmentation in isolated nuclei. This study examined the following: (a) the functional relationship between AP24 and the CPP32-like proteases of the casp...

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Detalhes bibliográficos
Main Authors: Wright, Susan C., Schellenberger, Ute, Wang, Hong, Kinder, David H., Talhouk, Jamil W., Larrick, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199070/
https://ncbi.nlm.nih.gov/pubmed/9314559
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