Regulation of Amyloid Precursor Protein Catabolism Involves the Mitogen-Activated Protein Kinase Signal Transduction Pathway

Catabolic processing of the amyloid precursor protein (APP) is subject to regulatory control by protein kinases. We hypothesized that this regulation involves sequential activation of the enzymes mitogen-activated protein kinase kinase (MEK) and extracellular signal-regulated protein kinase (ERK). I...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Mills, Julia, Laurent Charest, David, Lam, Fred, Beyreuther, Konrad, Ida, Nobuo, Pelech, Steven L., Reiner, Peter B.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 1997
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573401/
https://ncbi.nlm.nih.gov/pubmed/9390997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-24-09415.1997
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