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Regulation of Amyloid Precursor Protein Catabolism Involves the Mitogen-Activated Protein Kinase Signal Transduction Pathway

Catabolic processing of the amyloid precursor protein (APP) is subject to regulatory control by protein kinases. We hypothesized that this regulation involves sequential activation of the enzymes mitogen-activated protein kinase kinase (MEK) and extracellular signal-regulated protein kinase (ERK). I...

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Опубликовано в: :J Neurosci
Главные авторы: Mills, Julia, Laurent Charest, David, Lam, Fred, Beyreuther, Konrad, Ida, Nobuo, Pelech, Steven L., Reiner, Peter B.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 1997
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573401/
https://ncbi.nlm.nih.gov/pubmed/9390997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-24-09415.1997
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