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Regulation of Amyloid Precursor Protein Catabolism Involves the Mitogen-Activated Protein Kinase Signal Transduction Pathway

Catabolic processing of the amyloid precursor protein (APP) is subject to regulatory control by protein kinases. We hypothesized that this regulation involves sequential activation of the enzymes mitogen-activated protein kinase kinase (MEK) and extracellular signal-regulated protein kinase (ERK). I...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Mills, Julia, Laurent Charest, David, Lam, Fred, Beyreuther, Konrad, Ida, Nobuo, Pelech, Steven L., Reiner, Peter B.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573401/
https://ncbi.nlm.nih.gov/pubmed/9390997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-24-09415.1997
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