Regulation of Amyloid Precursor Protein Catabolism Involves the Mitogen-Activated Protein Kinase Signal Transduction Pathway

Catabolic processing of the amyloid precursor protein (APP) is subject to regulatory control by protein kinases. We hypothesized that this regulation involves sequential activation of the enzymes mitogen-activated protein kinase kinase (MEK) and extracellular signal-regulated protein kinase (ERK). I...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Mills, Julia, Laurent Charest, David, Lam, Fred, Beyreuther, Konrad, Ida, Nobuo, Pelech, Steven L., Reiner, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1997
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573401/
https://ncbi.nlm.nih.gov/pubmed/9390997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-24-09415.1997
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