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Mutant Superoxide Dismutase-1-Linked Familial Amyotrophic Lateral Sclerosis: Molecular Mechanisms of Neuronal Death and Protection
Mutations in human Cu/Zn superoxide dismutase-1 (SOD) cause ∼20% of cases of familial amyotrophic lateral sclerosis (FALS). We investigated the mechanism of mutant SOD-induced neuronal degeneration by expressing wild-type and mutant SODs in neuronal cells by means of infection with replication-defic...
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| Udgivet i: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6573090/ https://ncbi.nlm.nih.gov/pubmed/9348345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-22-08756.1997 |
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