Altered Thiol Chemistry in Human Amyotrophic Lateral Sclerosis-linked Mutants of Superoxide Dismutase 1

Neurodegenerative diseases share a common characteristic, the presence of intracellular or extracellular deposits of protein aggregates in nervous tissues. Amyotrophic Lateral Sclerosis (ALS) is a severe and fatal neurodegenerative disorder, which affects preferentially motoneurons. Changes in the r...

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Main Authors: Solsona, Carles, Kahn, Thomas B., Badilla, Carmen L., Álvarez-Zaldiernas, Cristina, Blasi, Juan, Fernandez, Julio M., Alegre-Cebollada, Jorge
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2014
主題:
Molecular Bases of Disease
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175315/
https://ncbi.nlm.nih.gov/pubmed/25096579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.565333
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