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Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis
There is emerging evidence for the existence of secretory pathways for superoxide dismutase (SOD1) mutants linked to amyotrophic lateral sclerosis (ALS) and for neurotoxicity of extracellular mutant SOD1. This evidence led us to test immunization protocols aiming to reduce the burden of extracellula...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1790867/ https://ncbi.nlm.nih.gov/pubmed/17277077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606201104 |
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