Ablation of Proliferating Microglia Does Not Affect Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis Caused by Mutant Superoxide Dismutase

Microglial activation is a hallmark of all neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). Here, a detailed characterization of the microglial cell population within the spinal cord of a mouse model of familial ALS was performed. Using flow cytometry, we detected three dist...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gowing, Genevíève, Philips, Thomas, Van Wijmeersch, Bart, Audet, Jean-Nicolas, Dewil, Maarten, Van Den Bosch, Ludo, Billiau, An D., Robberecht, Wim, Julien, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671032/
https://ncbi.nlm.nih.gov/pubmed/18842883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3494-08.2008
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