Mediator complex interaction partners organize the transcriptional network that defines neural stem cells

The Mediator complex regulates transcription by connecting enhancers to promoters. High Mediator binding density defines super enhancers, which regulate cell-identity genes and oncogenes. Protein interactions of Mediator may explain its role in these processes but have not been identified comprehens...

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Udgivet i:Nat Commun
Main Authors: Quevedo, Marti, Meert, Lize, Dekker, Mike R., Dekkers, Dick H. W., Brandsma, Johannes H., van den Berg, Debbie L. C., Ozgür, Zeliha, van IJcken, Wilfred F. J., Demmers, Jeroen, Fornerod, Maarten, Poot, Raymond A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573065/
https://ncbi.nlm.nih.gov/pubmed/31209209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10502-8
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