Mediator complex interaction partners organize the transcriptional network that defines neural stem cells

The Mediator complex regulates transcription by connecting enhancers to promoters. High Mediator binding density defines super enhancers, which regulate cell-identity genes and oncogenes. Protein interactions of Mediator may explain its role in these processes but have not been identified comprehens...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Quevedo, Marti, Meert, Lize, Dekker, Mike R., Dekkers, Dick H. W., Brandsma, Johannes H., van den Berg, Debbie L. C., Ozgür, Zeliha, van IJcken, Wilfred F. J., Demmers, Jeroen, Fornerod, Maarten, Poot, Raymond A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573065/
https://ncbi.nlm.nih.gov/pubmed/31209209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10502-8
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