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Mediator complex interaction partners organize the transcriptional network that defines neural stem cells
The Mediator complex regulates transcription by connecting enhancers to promoters. High Mediator binding density defines super enhancers, which regulate cell-identity genes and oncogenes. Protein interactions of Mediator may explain its role in these processes but have not been identified comprehens...
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| Опубликовано в: : | Nat Commun |
|---|---|
| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6573065/ https://ncbi.nlm.nih.gov/pubmed/31209209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10502-8 |
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