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Hepatocyte spheroids as an alternative to single cells for transplantation after ex vivo gene therapy in mice and pig models(✰)
BACKGROUND: Autologous hepatocyte transplantation after ex vivo gene therapy is an alternative to liver transplantation for metabolic liver disease. Here we evaluate ex vivo gene therapy followed by transplantation of single-cell or spheroid hepatocytes. METHODS: Pig and mouse hepatocytes were isola...
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| Udgivet i: | Surgery |
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| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6573031/ https://ncbi.nlm.nih.gov/pubmed/29884476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2018.04.012 |
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