Hepatocyte spheroids as an alternative to single cells for transplantation after ex vivo gene therapy in mice and pig models(✰)

BACKGROUND: Autologous hepatocyte transplantation after ex vivo gene therapy is an alternative to liver transplantation for metabolic liver disease. Here we evaluate ex vivo gene therapy followed by transplantation of single-cell or spheroid hepatocytes. METHODS: Pig and mouse hepatocytes were isola...

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Bibliografske podrobnosti
izdano v:Surgery
Main Authors: Nicolas, Clara T., Hickey, Raymond D., Allen, Kari L., Du, Zeji, Guthman, Rebekah M., Kaiser, Robert A., Amiot, Bruce, Bansal, Aditya, Pandey, Mukesh K., Suksanpaisan, Lukkana, DeGrado, Timothy R, Nyberg, Scott L., Lillegard, Joseph B.
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573031/
https://ncbi.nlm.nih.gov/pubmed/29884476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2018.04.012
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