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Hepatocyte spheroids as an alternative to single cells for transplantation after ex vivo gene therapy in mice and pig models(✰)

BACKGROUND: Autologous hepatocyte transplantation after ex vivo gene therapy is an alternative to liver transplantation for metabolic liver disease. Here we evaluate ex vivo gene therapy followed by transplantation of single-cell or spheroid hepatocytes. METHODS: Pig and mouse hepatocytes were isola...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Surgery
Egile Nagusiak: Nicolas, Clara T., Hickey, Raymond D., Allen, Kari L., Du, Zeji, Guthman, Rebekah M., Kaiser, Robert A., Amiot, Bruce, Bansal, Aditya, Pandey, Mukesh K., Suksanpaisan, Lukkana, DeGrado, Timothy R, Nyberg, Scott L., Lillegard, Joseph B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573031/
https://ncbi.nlm.nih.gov/pubmed/29884476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2018.04.012
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