Lentiviral Vector-mediated Gene Therapy of Hepatocytes Ex Vivo for Autologous Transplantation in Swine

Gene therapy is an ideal choice to cure many inborn errors of metabolism of the liver. Ex-vivo, lentiviral vectors have been used successfully in the treatment of many hematopoietic diseases in humans, as their use offers stable transgene expression due to the vector’s ability to integrate into the...

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Vydáno v:J Vis Exp
Hlavní autoři: Kaiser, Robert A., Mao, Shennen A., Glorioso, Jaime, Amiot, Bruce, Nicolas, Clara T, Allen, Kari L., Du, Zeji, VanLith, Caitlin J, Hickey, Raymond D., Nyberg, Scott L., Lillegard, Joseph B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573062/
https://ncbi.nlm.nih.gov/pubmed/30451238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58399
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