Convergent allostery in ribonucleotide reductase

Ribonucleotide reductases (RNRs) use a conserved radical-based mechanism to catalyze the conversion of ribonucleotides to deoxyribonucleotides. Within the RNR family, class Ib RNRs are notable for being largely restricted to bacteria, including many pathogens, and for lacking an evolutionarily mobil...

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Udgivet i:Nat Commun
Main Authors: Thomas, William C., Brooks, F. Phil, Burnim, Audrey A., Bacik, John-Paul, Stubbe, JoAnne, Kaelber, Jason T., Chen, James Z., Ando, Nozomi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572854/
https://ncbi.nlm.nih.gov/pubmed/31201319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10568-4
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