Convergent allostery in ribonucleotide reductase

Ribonucleotide reductases (RNRs) use a conserved radical-based mechanism to catalyze the conversion of ribonucleotides to deoxyribonucleotides. Within the RNR family, class Ib RNRs are notable for being largely restricted to bacteria, including many pathogens, and for lacking an evolutionarily mobil...

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Vydáno v:Nat Commun
Hlavní autoři: Thomas, William C., Brooks, F. Phil, Burnim, Audrey A., Bacik, John-Paul, Stubbe, JoAnne, Kaelber, Jason T., Chen, James Z., Ando, Nozomi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572854/
https://ncbi.nlm.nih.gov/pubmed/31201319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10568-4
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