Binding of α-synuclein oligomers to Cx32 facilitates protein uptake and transfer in neurons and oligodendrocytes

The intercellular transfer of alpha-synuclein (α-syn) has been implicated in the progression of Parkinson’s disease (PD) and multiple system atrophy (MSA). The cellular mechanisms underlying this process are now beginning to be elucidated. In this study, we demonstrate that the gap junction protein...

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Опубликовано в: :Acta Neuropathol
Главные авторы: Reyes, Juan F., Sackmann, Christopher, Hoffmann, Alana, Svenningsson, Per, Winkler, Jürgen, Ingelsson, Martin, Hallbeck, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2019
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Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570706/
https://ncbi.nlm.nih.gov/pubmed/30976973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02007-x
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