Binding of α-synuclein oligomers to Cx32 facilitates protein uptake and transfer in neurons and oligodendrocytes

The intercellular transfer of alpha-synuclein (α-syn) has been implicated in the progression of Parkinson’s disease (PD) and multiple system atrophy (MSA). The cellular mechanisms underlying this process are now beginning to be elucidated. In this study, we demonstrate that the gap junction protein...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Acta Neuropathol
Päätekijät: Reyes, Juan F., Sackmann, Christopher, Hoffmann, Alana, Svenningsson, Per, Winkler, Jürgen, Ingelsson, Martin, Hallbeck, Martin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Berlin Heidelberg 2019
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Original Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570706/
https://ncbi.nlm.nih.gov/pubmed/30976973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02007-x
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