Binding of α-synuclein oligomers to Cx32 facilitates protein uptake and transfer in neurons and oligodendrocytes

The intercellular transfer of alpha-synuclein (α-syn) has been implicated in the progression of Parkinson’s disease (PD) and multiple system atrophy (MSA). The cellular mechanisms underlying this process are now beginning to be elucidated. In this study, we demonstrate that the gap junction protein...

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Publicat a:Acta Neuropathol
Autors principals: Reyes, Juan F., Sackmann, Christopher, Hoffmann, Alana, Svenningsson, Per, Winkler, Jürgen, Ingelsson, Martin, Hallbeck, Martin
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2019
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570706/
https://ncbi.nlm.nih.gov/pubmed/30976973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02007-x
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