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Allele-Specific Inhibition of Histone Demethylases
Histone demethylases play a critical role in mammalian gene expression by removing methyl groups from lysine residues in degree- and site-specific manner. To specifically interrogate members and isoforms of this class of enzymes, we have developed demethylase variants with an expanded active site. T...
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| Publicado no: | Chembiochem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6570502/ https://ncbi.nlm.nih.gov/pubmed/30618116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800756 |
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