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Engineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein–Protein Interactions
Protein–protein interactions mediated by methyllysine are ubiquitous in biological systems. Specific perturbation of such interactions has remained a challenging endeavor. Herein, we describe an allele-specific strategy toward an engineered protein–protein interface orthogonal to the human proteome....
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6988089/ https://ncbi.nlm.nih.gov/pubmed/31518125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b05725 |
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