Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE*3-Leiden mice following myocardial ischemia-reperfusion injury

BACKGROUND: Hypercholesterolemia is a major risk factor for ischemic heart disease including acute myocardial infarction. However, long-term effects of hypercholesterolemia in a rodent myocardial ischemia-reperfusion injury model are unknown. Therefore, the effects of diet-induced hypercholesterolem...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Pluijmert, Niek J., den Haan, Melina C., van Zuylen, Vanessa L., Steendijk, Paul, de Boer, Hetty C., van Zonneveld, Anton J., Fibbe, Willem E., Schalij, Martin J., Quax, Paul H. A., Atsma, Douwe E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570022/
https://ncbi.nlm.nih.gov/pubmed/31199833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217582
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