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Effects on cardiac function, remodeling and inflammation following myocardial ischemia–reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice

Many novel therapies to treat myocardial infarction (MI), yielding promising results in animal models, nowadays failed in clinical trials for several reasons. The most used animal MI model is based on permanent ligation of the left anterior descending (LAD) coronary artery in healthy mice resulting...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pluijmert, Niek J., Bart, Cindy I., Bax, Wilhelmina H., Quax, Paul H. A., Atsma, Douwe E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7538581/
https://ncbi.nlm.nih.gov/pubmed/33024178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73608-w
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