Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE*3-Leiden mice following myocardial ischemia-reperfusion injury

BACKGROUND: Hypercholesterolemia is a major risk factor for ischemic heart disease including acute myocardial infarction. However, long-term effects of hypercholesterolemia in a rodent myocardial ischemia-reperfusion injury model are unknown. Therefore, the effects of diet-induced hypercholesterolem...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pluijmert, Niek J., den Haan, Melina C., van Zuylen, Vanessa L., Steendijk, Paul, de Boer, Hetty C., van Zonneveld, Anton J., Fibbe, Willem E., Schalij, Martin J., Quax, Paul H. A., Atsma, Douwe E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570022/
https://ncbi.nlm.nih.gov/pubmed/31199833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217582
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