Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE*3-Leiden mice following myocardial ischemia-reperfusion injury

BACKGROUND: Hypercholesterolemia is a major risk factor for ischemic heart disease including acute myocardial infarction. However, long-term effects of hypercholesterolemia in a rodent myocardial ischemia-reperfusion injury model are unknown. Therefore, the effects of diet-induced hypercholesterolem...

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Bibliographic Details
Published in:PLoS One
Main Authors: Pluijmert, Niek J., den Haan, Melina C., van Zuylen, Vanessa L., Steendijk, Paul, de Boer, Hetty C., van Zonneveld, Anton J., Fibbe, Willem E., Schalij, Martin J., Quax, Paul H. A., Atsma, Douwe E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570022/
https://ncbi.nlm.nih.gov/pubmed/31199833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217582
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