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Desensitization of acetylcholine receptors in rat myotubes is enhanced by agents that elevate intracellular cAMP

Incubating skeletal muscle fibers with forskolin, an activator of adenylate cyclase, increases the rate at which nicotinic acetylcholine receptors (AChRs) desensitize when exposed to ACh. Several reports indicate that this is due to the phosphorylation of AChRs by cAMP- dependent protein kinase, but...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Middleton, P, Rubin, LL, Schuetze, SM
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6569451/
https://ncbi.nlm.nih.gov/pubmed/2459325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.08-09-03405.1988
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