Effect of Elevated Intracellular cAMP Levels on Actomyosin Contraction in Bovine Trabecular Meshwork Cells

PURPOSE. Elevated cAMP in the trabecular meshwork (TM) cells increases the aqueous humor outflow facility. The authors investigated the mechanisms by which elevated cAMP opposes the RhoA-Rho kinase pathway, leading to the relaxation of the actomyosin system in bovine TM cells. METHODS. Forskolin (Fs...

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Bibliografiska uppgifter
Huvudupphovsmän: Ramachandran, Charanya, Patil, Rajkumar V., Sharif, Najam A., Srinivas, Sangly P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Association for Research in Vision and Ophthalmology, Inc. 2011
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101661/
https://ncbi.nlm.nih.gov/pubmed/21071747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6241
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