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Rho-Rho kinase pathway in the actomyosin contraction and cell-matrix adhesion in immortalized human trabecular meshwork cells

PURPOSE: The outflow facility for aqueous humor across the trabecular meshwork (TM) is enhanced by agents that oppose the actomyosin contraction of its resident cells. Phosphorylation of MYPT1 (myosin light chain [MLC] phosphatase complex of Type 1) at Thr853 and Thr696 inhibits dephosphorylation of...

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Autors principals: Ramachandran, C., Patil, R.V., Combrink, K., Sharif, N.A., Srinivas, S.P.
Format: Artigo
Idioma:Inglês
Publicat: Molecular Vision 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144732/
https://ncbi.nlm.nih.gov/pubmed/21850162
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