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Potassium restriction boosts vacuolar acidity and extends lifespan in yeast

Lysosome function is compromised during aging and in many disease states. Interventions that promote lysosomal activity and acidification are thus of prime interest as treatments for longevity and health. Intracellular pH can be controlled by the exchange of protons for inorganic ions, and in cells...

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Detalhes bibliográficos
Publicado no:Exp Gerontol
Main Authors: Sasikumar, Arjun N., Killilea, David W., Kennedy, Brian K., Brem, Rachel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568319/
https://ncbi.nlm.nih.gov/pubmed/30742903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2019.02.001
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