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Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino acid status

Reduced methionine (Met) intake can extend lifespan of rodents, but whether this regimen represents a general strategy for regulating aging has been controversial. Here we report that Met restriction extends lifespan in both fruit flies and yeast, and that this effect requires low amino acid status....

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lee, Byung Cheon, Kaya, Alaattin, Ma, Siming, Kim, Gwansu, Gerashchenko, Maxim V., Yim, Sun Hee, Hu, Zhen, Harshman, Lawrence G., Gladyshev, Vadim N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350766/
https://ncbi.nlm.nih.gov/pubmed/24710037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4592
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