Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino acid status

Reduced methionine (Met) intake can extend lifespan of rodents, but whether this regimen represents a general strategy for regulating aging has been controversial. Here we report that Met restriction extends lifespan in both fruit flies and yeast, and that this effect requires low amino acid status....

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Lee, Byung Cheon, Kaya, Alaattin, Ma, Siming, Kim, Gwansu, Gerashchenko, Maxim V., Yim, Sun Hee, Hu, Zhen, Harshman, Lawrence G., Gladyshev, Vadim N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350766/
https://ncbi.nlm.nih.gov/pubmed/24710037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4592
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