Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino acid status

Reduced methionine (Met) intake can extend lifespan of rodents, but whether this regimen represents a general strategy for regulating aging has been controversial. Here we report that Met restriction extends lifespan in both fruit flies and yeast, and that this effect requires low amino acid status....

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Bibliographic Details
Published in:Nat Commun
Main Authors: Lee, Byung Cheon, Kaya, Alaattin, Ma, Siming, Kim, Gwansu, Gerashchenko, Maxim V., Yim, Sun Hee, Hu, Zhen, Harshman, Lawrence G., Gladyshev, Vadim N.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350766/
https://ncbi.nlm.nih.gov/pubmed/24710037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4592
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